Surgical reduction of tumour bulk in management of abdominal Burkitt's lymphoma.
نویسندگان
چکیده
The results of a retrospective study of the value of reductive surgery in the treatment of abdominal Burkitt's lymphoma are reported. Nine patients had almost complete removal of the tumour, 16 had little over half of the tumour removed, and 43 underwent biopsy only. All patients subsequently received chemotherapy. There was a highly significant difference in the proportion of patients achieving a sustained durable remission (P > 0.0001) and a significant difference in survival (P > 0.05) between the group having almost complete removal and the partial resection group. Partial resection gave no advantage over no surgery. We believe that whenever possible complete removal of the abdominal tumour should be attempted regardless of the presence of extra-abdominal tumour; but unless at least 90% of the tumour can be removed there is no advantage in partial resection in terms of response to subsequent chemotherapy. In particular the removal of one of two involved ovaries can no longer be recommended. The implications of these results are related to cancer treatment strategy.
منابع مشابه
A 10 year study of surgical abdominal masses in university hospital No:1 Kerman university of medical sciences and health services
In order to determine the prevalence rate of abdominal masses in children referred to the Kerman university hospital number one from 1984 to 1994, the medical records of 51 of these children were reviewed. 27 of these patients were boys (53℅), and 24 were girls (47℅). The age variance of these patients were between 3 months and 14 years. In this study, the most common tumor was Wilm,s tumor ...
متن کامل-
There are some evidences on involvement of ABL2 in a number of cancers, especially ABL2 overexpression was observed in Raji, a Burkitt's lymphoma (BL) cell line. Therefore ABL2 overexpression may be involved in pathogenesis of Burkitt's lymphoma. The aim of this study was to evaluate ABL2 significance in BL. For this purpose 20 formaldehyde fixed paraffin embedded blocks – 16BL and 4 normal lym...
متن کاملAnticarcinogenic Activity of Leptadenia reticulata against Dalton’s Ascitic Lymphoma
The aim of the present study is to evaluate the effect of ethanolic extract of leaves of Leptadenia reticulata leaves (LELR) against Dalton’s Ascitic Lymphoma (DAL) in Swiss Albino mice. DAL cells were injected intraperitoneally (106 cells/mouse) to the mice. Two days after cells injection the animals were treated with 200 mg/kg of LELR for 8 days. Five-fluorouracil (20 mg/kg) was used ...
متن کاملIleocecal burkitt's lymphoma presenting as acute appendicitis: A case report
Introduction: Burkitt's lymphoma is a highly aggressive nonHodgkin lymphoma and occurs predominantly in the first decades of life in males. Often the clinical presentation is an abdominal mass associated with abdominal pain, nausea, intestinal obstruction or intussusceptions. The association between Burkitt's lymphoma and histological proven acute appendicitis is rare, and usually is secondary...
متن کاملIntrathecal chemotherapy in Burkitt's lymphoma.
Meningeal involvement with Burkitt lymphoma cells constitutes the most challenging therapeutic problem in the management of Burkitt's tumour. The results of intrathecal chemotherapy with methotrexate or cytosine arabinoside in 55 episodes of malignant pleocytosis in 38 patients with Burkitt's tumour are described. The response was complete in nearly all patients after the administration of eith...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- British medical journal
دوره 2 5914 شماره
صفحات -
تاریخ انتشار 1974